MID-IONIC CARBENES AND TRIAZOLES FOR USE IN ANTIBACTERIAL COMPOUNDS USING INFRARED SPECTROSCOPY: SYSTEMATIC REVIEW
Mid-ionic carbenes and triazoles are promising classes of compounds that show antibacterial activity. This systematic review evaluates the existing literature on using UV infrared spectroscopy to study mid-ionic carbenes and triazole compounds and their potential use as antibacterial agents. A systematic search of scientific databases identified 24 relevant studies. The reviewed studies demonstrated that UV infrared spectroscopy can be effectively used to characterize the structures and bonding properties of mid-ionic carbenes and triazoles. Some studies found certain mid-ionic carbenes and triazole derivatives exhibit antibacterial activity against common pathogens like Staphylococcus aureus and Escherichia coli based on in vitro assays. However, more research is still needed to understand structure-activity relationships and optimize these compounds for safe and effective use as novel antibacterial agents. This review summarizes the current state of research and highlights important areas for future investigation.
Keywords: mid-ionic carbenes, triazoles, antibacterial activity, UV infrared spectroscopy, systematic review