ASSOCIATION BETWEEN BIOCHEMICAL LEPTIN AND SOME BIOCHEMICAL MARKERS IN IRAQI PATIENTS WITH OBESITY AND PERIODONTAL
Abstract
The objective of the study is to correlate the relationship between body composition and the activity of the alpha-amylase enzyme in the saliva of healthy people and people with obesity which may provide further clues to investigate the potential regulation and biological mechanism of obesity. The results showed the gender of patients of the four groups revealed no significant differences in mean of gender (males and females) between the groups. Data showed that the there is a significant difference between the mean of patients with periodontal disease, the mean of age of patients of the four groups studied was ranged from 24.75 years in patients with obesity without periodontal disease group to 32.55 years in patients with obesity and periodontal disease group. Statements indicated that there is a significant difference between weight, BMI and groups studied. Data showed that ghrelin parameter varied in their effect on obesity and periodontal disease which seemed in their values of the tested four groups studied. The findings demonstrated that there is a significant difference in mean of insulin levels of groups studied; it seems that all the patients groups significantly decreased the level of insulin as compared with healthy control group. Patients with non-obesity and periodontal group recorded the lower value of insulin level (8.80 µU/ml) while patients with obesity and periodontal group recorded tha upper value of insulin level which recorded 14.48µU/ml with no significant differences with patients with obesity without periodontal group (14.48 vs. 10.24 µU/mL). Data demonstrated that there is a significant difference between the mean of FBS levels control group with the patients groups studied. The data revealed that the groups studied varied in their values of HbA1C levels with a normal range of this parameter (HbA1C).
Keywords: Obesity, Leptin, Ghrelin, Insulin resistance, TSH
